Standing out in the field of IgY Immunotechnology

  • Home
    Home A full collection of all the Research Archive entries.
  • Years
    Years Sort entries by year.
  • Tags
    Tags Displays a list of tags that have been used in the blog.
  • Archives
    Archives Contains a list of research entries that were created previously.

Magnetic lateral flow immunoassay test strip development – Considerations for proof of concept evaluation*

Posted by on in 2017
  • Font size: Larger Smaller
  • Hits: 434
  • Print

Connolly R1O' Kennedy R2. 2017. Methods. 116:132-140. doi: 10.1016/j.ymeth.2017.02.002. Epub 2017 Feb 16.

1
School of Biotechnology, Dublin City University, Glasnevin, Dublin 9, Ireland.
2
School of Biotechnology, Dublin City University, Glasnevin, Dublin 9, Ireland. Electronic address: richard.okennedy@dcu.ie.

Abstract

Lateral flow immunoassays (LFIA) have grown to become the predominant test device format for the diagnostics and point-of-care industries. The demand for robust and reproducible LFIAs has been facilitated through scale-up production methods using specialized and automated instruments. However, the feasibility of a LFIA device can still be evaluated in a small-scale laboratory setting through controlled manual preparation methods. The advent of super-paramagnetic (SPMP) labels for use in lateral flow has heralded the possibility of highly sensitive and stable LFIAs. The methods used for the preparation of a magnetic LFIA prototype device using a reserved suite of laboratory equipment are described.

*Note: Normal Chicken IgY antibodies used in this publication were produced by Gallus Immunotech Inc.

Buy it here:

KEYWORDS:

Lateral flow immunoassay; super-paramagnetic particles

PMID:
 
28213280
 
DOI:
 
10.1016/j.ymeth.2017.02.002
Last modified on